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Judie Alimonti |
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Country: |
Canada |
| Degree: |
BSc
Microbiology
PhD Immunology |
Supervisor:
Project Title: |
Dr.
Keith R. Fowke
Associate Professor,
Medical Microbilogy, University of Manitoba
HIV Specific CD4 Immune Responses |
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Description
of the Project: Approximately 5-10% of the women in the Pumwami (Nairobi, Kenya) commercial sex worker cohort have been identified as HIV resistant despite having up to 500 unprotected sexual exposures to HIV-infected clients. The cell mediated immune response plays a strong role in HIV resistance, and it is the CD4+ T helper (Th) cells that regulate this response. The Th cell contributes to viral clearance by governing the induction and magnitude of the CTL and humoral immune responses, as well as produce chemokines that inhibit HIV infection. Since Th cells have a role in viral resistance we examined the Th immune response in infected versus naturally resistant women enrolled in the Pumwami cohort in Nairobi. We hypothesize that the HIV specific Th responses in resistant individuals are qualitatively and quantitatively different from HIV infected individuals. |
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Joyee Antony George |
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Country: |
India |
| Degree: |
MSc.
Microbiology, M.S. University, India
Ph.D. Microbilogy, University of Madras, India |
Supervisor:
Project Title: |
Dr. Xi Yang, M.D., Ph.D.
Associate Professor,
Medical Microbilogy, University of Manitoba
Immune responses in chlamydial infection |
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Description
of the Project: The study will focus on investigating the immune responses in chlamydial infection. The role of cytokines and T-cell mediated responses will be studied. The elucidation of mechanisms of protective and pathological responses to chlamydial infection would provide a clearer understanding of the immunological basis of chlamydial infection, which would ultimately help in designing effective vaccine candidates for Chlamydia. |
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| Javier
Mignone |
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Country: |
Argentina
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| Degree: |
MSc
Health Services Administration, University
of Albert |
Supervisor:
Project Title:
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Dr. Stephen Moses
Professor, Medical Microbiology, University of Manitoba
Community level risk factors of HIV/AIDS in rural India
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Description
of the Project: The project will take place in
rural Karnataka, India. The study will seek
to answer the following question: Are underlying
factors,
such as caste structure, migration, levels of poverty,
social capital, types of employment, relations among different
religions, etc., impacting more proximate factors (e.g.,
risk behaviour, sex work, sexually transmitted infections,
etc.) and ultimately impacting HIV/AIDS rates? The study
will first develop and pre-test village-level data collection
tools. It will then conduct a data collection process from
a sample frame of 7500 villages. The data will be analyzed
for reliability and validity purposes. Further analyses
will test hypotheses of community level risk factors for
HIV/AIDS.
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